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Your request to link to MMDB for Heat shock protein HSP 90-alpha
| MMDB Description | |
|---|---|
| 12182 | Hsp90 N-terminal Domain Bound to Adp-mg |
| 23110 | Human Hsp90 in Complex With 17-desmethoxy-17-n,n- Dimethylaminoethylamino-geldanamycin |
| 28386 | Human Hsp90-alpha With 9-butyl-8-(3,4,5-trimethoxy-benzyl)- 9h-purin-6-ylamine |
| 28387 | Human Hsp90-alpha With 9-butyl-8-(4-methoxy-benzyl)-9h- Purin-6-ylamine |
| 28388 | Human Hsp90-alpha With 9-butyl-8-(3-trimethoxy-benzyl)-9h-purin-6ylamine |
| 28389 | Human Hsp90-alpha With 8-benzo[1,3]dioxol-,5-ylmethyl-9-butyl-9h-purin-6-ylamine |
| 28390 | Human Hsp90-alpha With 9-butyl-8-(2,5-dimethoxy-benzyl)-9h-purin-6-ylamine |
| 28391 | Human Hsp90-alpha With 9-butyl-8- (2-chloro-3,4,5-trimethoxy-benzyl)-9h-purin-6-ylamine |
| 28392 | Human Hsp90-alpha With 8-(2-chloro-3,4,5-trimethoxy-benzyl)- 9-pent-4-ylnyl-9h-purin-6-ylamine |
| 28393 | Human Hsp90-alpha With 8-(2-chloro-3,4,5-trimethoxy-benzyl) -2-fluoro-9-pent-4-ylnyl-9h-purin-6-ylamine |
| 28394 | Human Hsp90-alpha With 8-(2,5-dimethoxy-benzyl)-2-fluoro-9h-purin-6-ylamine |
| 28395 | Human Hsp90-alpha With 9-butyl-8-(2,5-dimethoxy-benzyl)-2- Fluoro-9h-purin-6-ylamine |
| 31201 | Human Hsp90-alpha With 8-(2,5-dimethoxy-benzyl)-2-fluoro-9- Pent-9h-purin-6-ylamine |
| 28397 | Human Hsp90-alpha With 8-benzo[1,3]dioxol-,5-ylmethyl-9-but Yl-2-fluoro-9h-purin-6-ylamine |
| 28398 | Structure-activity Relationships in Purine-based Inhibitor Binding to Hsp90 Isoforms |
| 29167 | Human Hsp90-beta With PU3 (9-butyl-8(3,4,5-trimethoxy- Benzyl)-9h-purin-6-ylamine) |
| 32056 | Crystal Structures of Human Hsp90alpha Complexed With Dihydroxyphenylpyrazoles |
| 32057 | Crystal Structure of Human Hsp90alpha Complexed With Dihydroxyphenylpyrazoles |
| 32058 | Crystal Structure of Human Hsp90alpha Complexed With Dihydroxyphenylpyrazoles |
| 52122 | Human Hsp90 Geldanamycin-binding Domain, "closed" Conformation |
| 52123 | Human Hsp90 Geldanamycin-binding Domain, "open" Conformation |
| 52124 | Geldanamycin Bound to the Hsp90 Geldanamycin-binding Domain |
| 34017 | Novel, Potent Small Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered Through Structure-based Design |
| 34019 | Novel, Potent Small Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered Through Structure-based Design |
| 35764 | 3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone |
| 35765 | 3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone |
| 35771 | Structure-based Discovery of a NEW Class of Hsp90 Inhibitors |
| 37644 | Human Hsp90 With 4-chloro-6-(4-piperazin-1-yl-1h-pyrazol-3- Yl)-benzene-1,2-diol |
| 37645 | Human Hsp90 With 5-(5-chloro-2,4-dihydroxy-phenyl)-4- Piperazin-1-yl-2h-pyrazole-3-carboxylic Acid Ethylamide |
| 37646 | Human Hsp90 With 4-chloro-6-(4-(4-(4-methanesulphonyl- Benzyl)-pierazin-1-yl)-1h-pyrazol-3-yl)-benzene-1,3-diol |
| 41514 | Structure of Human Hsp90-alpha Bound to the Potent Water Soluble Inhibitor Pu-h64 |
| 41515 | Structure of Human Hsp90-alpha Bound to the Potent Water Soluble Inhibitor Pu-h71 |
| 41606 | Structure of Human Hsp90-alpha Bound to the Potent Water Soluble Inhibitor Pu-dz8 |
| 65429 | Hsp90 Alpha Atpase Domain With Bound Small Molecule Fragment |
| 68330 | Human Cdc37-hsp90 Docking Model Based on NMR |
| 65169 | Hsp90 Complexed With A56322 |
| 65170 | Hsp90 Complexed With A143571 and A516383 |
| 65175 | Hsp90 Complexed With A943037 |
| 65176 | Hsp90 Complexed With A917985 |
| 54332 | Inhibition of the Hsp90 Molecular Chaperone in Vitro and in Vivo by Novel, Synthetic, Potent Resorcinylic Pyrazole, Isoxazole Amide Analogs |
| 61247 | 4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer |
| 61248 | 4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer |
| 75543 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 75544 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 75545 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 75546 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 75547 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 75548 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 75549 | Orally Active 2-amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone |
| 83922 | Structure of Hsp90 With an Inhibitor Bound |
| 84508 | Structure of Hsp90 With Small Molecule Inhibitor Bound |
| 84509 | Structure of Hsp90 With Small Molecule Inhibitor Bound |
| 84510 | Structre of Hsp90 With Small Molecule Inhibitor Bound |
| 84511 | Structre of Hsp90 With Small Molecule Inhibitor Bound |
| 84512 | Structre of Hsp90 With Small Molecule Inhibitor Bound |
| 84513 | Structure of Hsp90 With Small Molecule Inhibitor Bound |
| 84514 | Structure of Hsp90 With Small Molecule Inhibitor Bound |
| 84515 | Structure of Hsp90 With Small Molecule Inhibitor Bound |
| 83933 | Structure of Hsp90 With Small Molecule Inhibitor Bound |
| 83934 | Structre of Hsp90 With Small Molecule Inhibitor Bound |
| 83935 | Structre of Hsp90 With Small Molecule Inhibitor Bound |
| 84518 | Structre of Hsp90 With Small Molecule Inhibitor Bound |
| 65387 | Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Hsp90 |
| 65388 | Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Hsp90 |
| 65011 | Crystal Structure of Benzamide Tetrahydro-4h-carbazol-4-one Bound to Hsp90 |
| 68156 | Dihydroxylphenyl Amides as Inhibitors of the Hsp90 Molecular Chaperone |
| 68157 | Dihydroxylphenyl Amides as Inhibitors of the Hsp90 Molecular Chaperone |
| 72466 | Structure of Hsp90 Bound With a Novel Fragment |
| 74958 | Structure of Hsp90 Bound With a Noval Fragment |
| 77028 | Hsp90 N-terminal Domain in Complex With 1-{4-[(2r)-1-(5- Chloro-2,4-dihydroxybenzoyl)pyrrolidin-2-yl]benzyl}-3,3- Difluoropyrrolidinium |
| 75332 | Human Heat-shock Protein 90 (Hsp90) in Complex With {4-[3- (2,4-dihydroxy-5-isopropyl-phenyl)-5-thioxo- 1,5-dihydro- [1,2,4]triazol-4-yl]-benzyl}-carbamic Acid Ethyl Ester {ZK 2819} |
| 83294 | Crystal Structure of Hsp90 With Fragment 37-d04 |
| 83295 | Crystal Structure of Hsp90 With Fragment 42-c03 |
| 83296 | Crystal Structure of Hsp90 With Fragments 37-d04 and 42-c03 |
| 83297 | Crystal Structure of Hsp90 With Fragment Z064 |
| 84133 | Hsp90 N-terminal Domain With Pochoxime a |
| 84134 | Hsp90 N-terminal Domain With Pochoxime B |
| 79979 | Hsp90 N-terminal Domain in Complex With 4-chloro-6-{[(2r)-2- (2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol |
| 79980 | Hsp90 N-terminal Domain in Complex With (1r)-2-(5-chloro-2, 4-dihydroxybenzoyl)-n-ethylisoindoline-1-carboxamide |
| 79981 | Hsp90 N-terminal Domain in Complex With 4-(1,3-dihydro-2h- Isoindol-2-ylcarbonyl)benzene-1,3-diol |
| 84013 | Crystal Structure of Benzamide Snx-1321 Bound to Hsp90 |
| 87463 | Hsp90b N-terminal Domain in Complex With Ec44, a Pyrrolo-pyrimidine Methoxypyridine Inhibitor |
| 87396 | Crystal Structure of the Middle Domain of Human Hsp90-beta Refined at 2.3 Å Resolution |
| 90997 | Crystal Structure of Human Mc-hsp90 in C2221 Space Group |
| 90998 | Crystal Structure of Human Mc-hsp90 in P21 Space Group |
| 89736 | Design and SAR of Macrocyclic Hsp90 Inhibitors With Increased Metabolic Stability and Potent Cell-proliferation Activity |
| 90213 | Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-amino-4-{4-chloro-2-[2-(4- Fluoro-1h-pyrazol-1-yl)ethoxy]-6-methylphenyl}-n-(2,2- Difluoropropyl)-5,7-dihydro-6h-pyrrolo[3,4-d]pyrimidine-6-carboxamide |
| 90214 | Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-amino-4-{4-chloro-2-[2-(4- Fluoro-1h-pyrazol-1-yl)ethoxy]-6-methylphenyl}-n-(2,2- Difluoropropyl)-5,7-dihydro-6h-pyrrolo[3,4-d]pyrimidine-6-carboxamide |
| 90215 | Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-amino-4-{4-chloro-2-[2-(4- Fluoro-1h-pyrazol-1-yl)ethoxy]-6-methylphenyl}-n-(2,2- Difluoropropyl)-5,7-dihydro-6h-pyrrolo[3,4-d]pyrimidine-6-carboxamide |
| 90216 | Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-amino-4-{4-chloro-2-[2-(4- Fluoro-1h-pyrazol-1-yl)ethoxy]-6-methylphenyl}-n-(2,2- Difluoropropyl)-5,7-dihydro-6h-pyrrolo[3,4-d]pyrimidine-6-carboxamide |
| 90498 | Macrocyclic Lactams as Potent Hsp90 Inhibitors With Excellent Tumor Exposure and Extended Biomarker Activity |
| 91246 | Discovery of a Macrocyclic O-aminobenzamide Hsp90 Inhibitor With Heterocyclic Tether That Shows Extended Biomarker Activity and in Vivo Efficacy in a Mouse Xenograft Model |
| 91261 | Co-crystal Structure of the Hsp90 ATP Binding Domain in Complex With 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine |
| 91262 | Co-crystal Structure of the Hsp90 ATP Binding Domain in Complex With 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7h-pyrrolo[2,3- D]pyrimidine-5- Carbonitrile |
| 91263 | Co-crystal Structure of the Hsp90 ATP Binding Domain in Complex With 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7h-pyrrolo[2,3- D]pyrimidine-5-carbonitrile |